HPE ProLiant DL380 Gen11 Intel Xeon Rack GPU Server

The HPE ProLiant DL380 Gen11 Intel Xeon Rack GPU Server is an enterprise-class, performance-driven server engineered for today’s demanding workloads, including AI, machine learning, data analytics, virtualization, and HPC environments. Powered by 4th- or 5th-generation Intel Xeon Scalable processors, the system supports up to 64 cores per CPU, enabling powerful multi-threaded performance for compute-intensive applications. With 32 DIMM slots and support for up to 8 TB of DDR5 ECC memory, it delivers exceptional bandwidth and stability for memory-heavy workloads such as large databases and virtualization clusters.

The DL380 Gen11 offers extensive storage flexibility, supporting SAS, SATA, NVMe, and multiple drive-bay configurations, making it suitable for both high-capacity and high-performance deployments. Its PCIe Gen5 architecture provides significant bandwidth for accelerators, fast SSDs, and high-speed networking. The server is also GPU-optimized, supporting multiple GPUs including single-wide and double-wide cards, making it an excellent platform for AI training, inference, and scientific computing.

Built-in management through HPE iLO 6 ensures advanced remote monitoring, automation, and security. Features such as Silicon Root of Trust, TPM, and Secure Boot deliver strong protection for critical workloads. With its balanced design, scalability, and GPU capabilities, the DL380 Gen11 is a top choice for modern enterprise and data-center environments.

Key Features

• Powered by 4th/5th Gen Intel® Xeon Scalable Processors for high-performance computing
• Supports multiple GPUs, ideal for AI, ML, VDI, and high-density graphics workloads
• Up to 32 DIMM slots with DDR5 memory for increased bandwidth and energy efficiency
• Flexible storage options: NVMe, SAS, and SATA with hot-plug support
• Advanced iLO 6 management for remote monitoring, automation, and enhanced security
• Redundant Platinum power supplies for high availability
• Scalable architecture suitable for enterprise, data-center, and cloud workloads
• Enhanced hardware security features including Silicon Root of Trust
• High-speed network support with OCP 3.0 adapters

Where It Can Be Used?

• AI & Machine Learning Workloads: Leverages GPU acceleration for model training and inference
• Virtualization & Cloud Infrastructure: Ideal for VMware, Hyper-V, and container platforms
• Data Center Applications: High reliability and scalability for mission-critical tasks
• High-Performance Computing (HPC): Efficient processing for scientific and engineering workloads
• Enterprise Applications: Database servers, ERP systems, and large-scale business operations
• Edge & Hybrid IT Environments: Suitable for organizations scaling between on-prem and cloud

Installation Steps

1. Unbox & Inspect: Verify server components, rail kit, and power accessories.
2. Rack Mount: Install the rails, then slide the server into the rack securely.
3. Connect Power & Network: Attach redundant power cables and network/management cables.
4. Install Drives & GPUs (If Needed): Insert NVMe/SAS/SATA drives and GPU units.
5. Boot & Access iLO: Power on the server and configure management settings via iLO.
6. Configure BIOS/RAID: Set performance profiles and create RAID arrays for storage.
7. Install OS: Deploy your preferred OS such as Windows Server, Linux, or VMware ESXi.
8. Finalize Setup: Apply firmware updates, configure security, and optimize performance profiles.

Specification Table